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Lisinopril Side EffectsIn SummaryCommonly reported side effects of lisinopril include: dizziness, hypotension, hyperkalemia, increased blood urea nitrogen, and increased serum creatinine. Other side effects include: headache. See below for a comprehensive list of adverse effects.For the ConsumerApplies to lisinopril: oral solution, oral tabletWarningOral route (Tablet; Solution)Discontinue lisinopril as soon as possible when pregnancy is detected, as drugs that act directly on the renin-angiotensin system can cause injury and death to the developing fetus.Side effects requiring immediate medical attentionAlong with its needed effects, lisinopril may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.Check with your doctor immediately if any of the following side effects occur while taking lisinopril:More commonBlurred visioncloudy urineconfusiondecrease in urine output or decrease in urine-concentrating abilitydizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting positionsweatingunusual tiredness or weaknessLess commonAbdominal or stomach painbody aches or painchest painchillscommon coldcoughdiarrheadifficulty breathingear congestionfeverheadacheloss of voicenasal congestionnausearunny nosesneezingsore throatvomitingRareArm, back, or jaw painchest discomfort, tightness, or heavinessfast or irregular heartbeatgeneral feeling of discomfort or illnessjoint painloss of appetitemuscle aches and painsshiveringtrouble sleepingSide effects not requiring immediate medical attentionSome side effects of lisinopril may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:Less commonDecreased interest in sexual intercourseinability to have or keep an erectionlack or loss of strengthloss in sexual ability, desire, drive, or performancerashRareAcid or sour stomachbelchingburning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelingsfeeling of constant movement of self or surroundingsheartburnindigestionmuscle crampssensation of spinningstomach discomfort or upsetswellingFor Healthcare ProfessionalsApplies to lisinopril: oral solution, oral tabletCardiovascularVery common (10% or more): Hypotension (11%)Common (1% to 10%): Chest pain, angina pectoris, orthostatic hypotension, palpitationsUncommon (0.1% to 1%): Angioneurotic edema, myocardial infarction or cerebrovascular accident, palpitations, tachycardia, Raynaud's phenomenonHypotension is most likely in patients who are sodium and intravascular volume depleted. In large studies, patients have reported "heart pounding" and chest pain, although the relationship to lisinopril is questionable.RenalCommon (1% to 10%): Creatinine increased (10%)Very rare (less than 0.01%): Renal insufficiencyNervous systemVery common (10% or more): Dizziness (19%)Common (1% to 10%): Headache, syncopeUncommon (0.1% to 1%): ParesthesiasRespiratoryCommon (1% to 10%): Creatinine increased (10%)Uncommon (0.1% to 1%): RhinitisVery rare (less than 0.01%): Bronchospasm, sinusitis, allergic alveolitis/eosinophilic pneumoniaA study has revealed a significantly higher incidence of discontinuation of angiotensin converting enzyme inhibitor therapy due to cough among black patients compared with nonblack patients (9.6% vs. 2.4%).MetabolicCommon (1% to 10%): HyperkalemiaFrequency not reported: Gout, hypoglycemia in diabetic patients receiving ACE inhibitors when concurrently treated with oral antidiabetic agents or insulinGastrointestinalCommon (1% to 10%): Diarrhea, nausea, vomitingFrequency not reported: Pancreatitis, constipation, flatulence, dry mouth, taste disturbanceHypersensitivityUncommon (0.1% to 1%): AngioedemaDermatologicUncommon (0.1% to 1%): Rash, pruritus, erythemaRare (0.01% to 0.1%): Alopecia, urticaria, psoriasis, hypersensitivity/angioedema, angioneurotic edema of the face, extremities, lips, tongue, glottis, and/or larynxVery rare (less than 0.01%): Sweating, skin lesions, skin infections, pemphigus, toxic epidermal necrolysis, Stevens-Johnson Syndrome, erythema multiforme, cutaneous pseudolymphomaFrequency not reported: Photosensitivity, flushing, diaphoresisHematologicVery rare (less than 0.01%): Bone marrow depression, hemolytic anemia, leukopenia/neutropenia, thrombocytopenia, decreases in hemoglobin, decreases in hematocritPsychiatricRare (0.01% to 0.1%): Memory impairment, confusion, somnolence, irritability, nervousness, hallucinationsVery rare (less than 0.01%): ManiaHepaticCommon (1% to 10%): Creatinine increasedVery rare (less than 0.01%): Cholestatic jaundice that progresses to fulminant hepatic necrosis and sometimes death (discontinue of therapy if jaundice or markedly elevated hepatic serum enzymes develop)EndocrineVery rare (less than 0.01%): Diabetes, syndrome of inappropriate antidiuretic hormone secretion (SIADH)OtherCommon (1% to 10%): CoughFrequency not reported: Fatigue, asthenia, orthostatic effects, tinnitus, olfactory disturbanceGenitourinaryUncommon (0.1% to 1%): ImpotenceRare (less than 0.1%): GynecomastiaFrequency not reported: ProteinuriaInformation by https://www.drugs.com/sfx/lisinopril-side-effects.html